I heard somewhere today that Pamela Anderson was originally offered the role of Dana Scully (X-Files). Gillian Anderson, the real Scully says:
"They were looking for someone bustier, taller, leggier than me. They
couldn't fathom how David and me could equal success. At the beginning,
nobody trusted that I could do anything. I had no body of work behind me at
all, and, certainly Fox felt very strongly that I wasn't the right person
for the job."
Oh, what a mistake it would have been.